研究成果

Xie Y*, Zhu Y*, Wang N*, Luo M, Ota T, Guo R, Yu Z, Aizezi Y, Zhang L, Zhang Y, Bao H, Wang Y, Zhu Z, Huang A, Zhao Y, Asami T, Huang H, Guo H^#, and Jiang K^#. Chemical genetic screening identifies nalacin as an inhibitor of GH3 amido synthetase for auxin conjugation.

PNAS

. 2022, 119 (49) e2209256119. （中科院1区, Nature Index）

Aizezi Y, Zhao H, Zhang Z, Bi Y, Yang Q, Guo G, Zhang H, Guo H, Jiang K^# and Wang Z^#. Structure-based virtual screening identifies small molecule inhibitors of O-fucosyltransferase SPINDLY.

Plant Cell

. 2024, 36(3): 479-509. （中科院1区, Nature Index）

Jiang K^#, Guo H, and Zhai J^#. Interplay of phytohormones and epigenetic regulation: A recipe for plant development and plasticity.

JIPB

. 2023, 65(2): 381-398. （中科院1区）

Aizezi Y, Shu H, Zhang L, Zhao H, Peng Y, Lan H, Xie Y, Li J, Wang Y, Guo H^#, and Jiang K^#. Cytokinin regulates apical hook development via the coordinated actions of EIN3/EIL1 and PIF transcription factors in Arabidopsis.

J Exp Bot

. 2022, 73(1): 213-227. (封面文章) （中科院1区）

Ke D*, Xie Y*, Li H, Hu L, He Y, Guo C, Zhai Y, Guo J, Li K, Chu Z, Zhang J, Zhang X, Al-Balili S, Jiang K^#, Miao Y^#, Jia K^#. Anchorene, a carotenoid-derived growth regulator, modulates auxin homeostasis by suppressing GH3-mediated auxin conjugation.

JIPB

. 2024, 66(11): 2490-2504. （中科院1区）

Aizezi Y, Xie Y, Guo H^#, and Jiang K^#. New wine in an old bottle: utilizing chemical genetics to dissect apical hook development.

Life

. 2022, 12(8), 1285. （中科院4区）

Yu Y and Jiang K^#. Metabolic mediators at the nexus: how SAM, acetyl-CoA, and NAD+ bridge phytohormone signaling and epigenetic regulation.

Curr Opin Plant Biol

. 2026, 89:102832. （中科院1区）

Jiang K^*, Wang J^*, Ito S, Takahashi I, Ohta T, Murase K, Nakajima M, Guo H, Takayama S, Asami T^#. Analysis of the physiological roles and mode of actions of phthalimides as GA signal regulator in rice.

J Plant Growth Regul

. 2023, 42: 2637-2645. （中科院3区）

Zhu Y, Li H, Su Q, Wen J, Wang Y, Song W, Xie Y, He W, Yang Z, Jiang K^#, Guo H^#. A phenotype-directed chemical screen identifies ponalrestat as an inhibitor of the plant flavin monooxygenase YUCCA in auxin biosynthesis.

J Biol Chem

. 2019, 294(52): 19923-19933. （中科院2区, Nature Index）

Jiang K^*, Otani M^*, Shimotakahara H, Yoon JM, Park SH, Miyaji T, Nakano T, Nakamura H, Nakajima M, Asami T^#. Substituted phthalimide AC94377 is a selective agonist of the gibberellin receptor GID1.

Plant Physiol

. 2017, 173(1): 825-835. （中科院1区）

Takeuchi J^*, Jiang K^*, Hirabayashi K^*, Imamura Y, Wu Y, Xu Y, Miyakawa T, Nakamura H, Tanokura M, Asami T^#. Rationally Designed Strigolactone Analogs as Antagonists of the D14 Receptor.

Plant Cell Physiol

. 2018, 59(8): 1545-1554. （中科院2区）

Jiang K and Asami T^#. Chemical regulators of plant hormones and their applications in basic research and agriculture.

Biosci Biotechnol Biochem

. 2018, 82(8): 1265-1300. (封面文章) （中科院4区）

Jiang K, Kurimoto T, Seo EK, Miyazaki S, Nakajima M, Nakamura H, Asami T^#. Development of Inhibitors of Salicylic Acid Signaling.

J Agric Food Chem

. 2015, 63(32): 7124-33. （中科院2区）

Tian M^*, Jiang K^*, Takahashi I, Li G^#. Strigolactone-induced senescence of a bamboo leaf in the dark is alleviated by exogenous sugar.

J Pestic Sci

. 2018, 43(3): 173-179. （中科院4区）

Jiang K*, Shimotakahara H*, Luo M*, Otani M, Nakamura H, Moselhy SS, Abualnaja KO, Al-Malki AL, Kumosani TA, Kitahata N, Nakano T, Nakajima M, Asami T^#. Chemical screening and development of novel gibberellin mimics.

Bioorg Med Chem Lett

. 2017, 27(16): 3678-3682. （中科院4区）

Zeb M*, Zhou X*, Wang M, Kong Y, Zhang X, Ni D, Tu W, Li X^#, Jiang K^#, Xiao W^#. Isolation and structural characterization of a novel benzoxepine derivative with a unique 7/6/5/5-fused ring system.

J Mol Struct

. 2025, 1328, 141291. （中科院2区）

Zeb M*, Lai J*, Zhang X*, Wang L, Wang M, Kong Y, Li X^#, Jiang K^#, Xiao W^#. Five new clerodane diterpenoids from Callicarpa integerrima and their anti-inflammatory activity.

Fitoterapia

. 2025, 186, 106857. （中科院3区）

Hao D, Xiao Z, Yan W, Pan C, Yang Y, Song W, Chen Z, Xing Y, Jin L, Peng Y, Qiu Y, Jiang K, Wen X, Huang K, Xiao S, Chen H, Guo H^#. Sensing endoplasmic reticulum redox state by ethylene receptors.

Cell

. 189, 1-19. （中科院1区, Nature Index）

Wang C, Chi C, Liu Y, Zhao J, Wang Q, Wang N, Zhang Z, Jiang K, Xue Y, Li Y, et al. Molecular basis of DRB4-assisted long RNA processing and 21-nt siRNA biogenesis by DCL4 in plants.

Nature Plants

. 2026, in press. （中科院1区）

Yan Y, Tian B, Li X, Wang Y, Shi Y, Jiang K, Zhai R, Davies K, Ma F, Atkinson R, Li P. The polyphenol trade-off: leaf protection vs fruit attraction in apples driven by the phlorizin glycosyltransferase PGGT1.

New Phytol

. 2026, 250: 591-601. （中科院1区）

Zhang H, Zhang B, Zhao Y, Su Y, Peng Y, Yang X, Zhao H, Liu H, Feng J, Pei H, Zhang W, Huang N, Jiang K, Ito M, Liu G, Jork N, Anderson K, Nagata E, Jessen H, Hawkings P, Du C, Rao F. Oncometabolite 5-IP7 inhibits inositol 5-phosphatase to license E-cadherin endocytosis.

Nat Chem Biol

. 2026, 22, 293-306. （中科院1区, Nature Index）

Wang J, Takahashi I, Kikuzato K, Sakai T, Zhu Z, Jiang K, Nakamura H, Nakano T, Tanokura M, Miyakawa T, Asami T. Identification and structure-guided development of triazole urea-based selective antagonists of Arabidopsis karrikin signaling.

Nat Commun

. 2025, 16(104). （中科院1区）

Liang W, Huang S, Chen X, Jiang K, Gong X, Guo H, Li L. The small-molecule pifithrin-alpha deactivates ETR1 to repress shade avoidance in Arabidopsis.

Sci Adv

. 2025, 11(33), 1-11. （中科院1区, Nature Index）

Chen W, Yan W, Jiang K, Huang H. Molecular insights into DNA recognition by HD-Zip transcription factors.

Plant Physiol

. 2025, 198, kiaf292. （中科院1区）

Yang Y, Kong Q, Liu C, Wang F, Li M, Li S, Shi Y, Krall L, Wang X, He S, Jiang K, Wu X, Yang M, Yang C. Homocysteine disrupts lysosomal function by V-ATPase inhibition.

J Cell Biol

. 2026, 225 (1): e202503081. （中科院1区）

Wang Y, Chen X, Guan Z, Yang L, Xiang D, Yan W, Jiang K, Liang C. Characterization of yellow-green leaf1 mutant for improved phosphorus use efficiency and rapid offspring screening in Tartary buckwheat.

Crop Sci

. 2023, 63(2): 803-816. （中科院3区）

Liu C, Hao D, Sun R, Zhang Y, Peng Y, Yuan Y, Jiang K, Li W, Wen X^#, and Guo H^#. Arabidopsis NPF2.13 functions as a critical transporter of bacterial natural compound tunicamycin in plant-microbe interaction.

New Phytol

. 2023, 238:765-780. （中科院1区）

Liu L*, Song W*, Huang S, Jiang K, Moriwaki Y, Wang Y, Men Y, Zhang D, Wen X, Han Z, Chai J^#, Guo H^#. Extracellular pH sensing by plant cell-surface peptide-receptor complexes.

Cell

. 2022, 185(18), 3341-3355. （中科院1区, Nature Index）

Zheng L, Meng J, Jiang K, Lan H, Wang Z, Lin M, Li W, Guo H, Wei Y^#, and Mu Y^#. Improving protein-ligand docking and screening accuracies by incorporating a scoring function correction term.

Brief Bioinform

. 2022, 23(3), 1-15. （中科院1区）

Zhou Y, Zhong Y, Li L, Jiang K, Gao J, Zhong K^#, Pan M^#, and Yan B. A multifunctional chitosan-derived conformal coating for the preservation of passion fruit.

LWT-Food Sci Technol

. 2022, 163, 113584. （中科院2区）

Oh K^# and Jiang K. Synthesis of fluorescently labeled pyrazole derivative inducing a triple response in Arabidopsis seedlings.

J Pestic Sci

. 2022, 47(4), 203-207. （中科院4区）

Watanabe D*, Takahashi I*, Jaroensanti-Tanaka N, Miyazaki S, Jiang K, Nakayasu M, Wada M, Asami T, Mizutani M, Okada K, Nakajima M. The apple gene responsible for columnar tree shape reduces the abundance of biologically active gibberellin.

Plant J

. 2021, 105:1026-1034. （中科院1区）

Takahashi I, Jiang K, and Asami T^#. Counteractive effects of sugar and strigolactone on leaf senescence of rice in darkness.

Agronomy

. 2021, 11(6), 1044. （中科院3区）

Nakamura H*, Hirabayashi K*, Miyakawa T, Kikuzato K, Hu W, Xu Y, Jiang K, Takahashi I, Niiyama R, Dohmae N, Tanokura M, Asami T^#. Triazole ureas covalently bind to strigolactone receptor and antagonize strigolactone responses.

Mol Plant

. 2019, 12(1):44-58. （中科院1区）

Jamil M, Kountche BA, Haider I, Guo X, Ntui VO, Jia KP, Ali S, Hameed US, Nakamura H, Lyu Y, Jiang K, Hirabayashi K, Tanokura M, Arold ST, Asami T, Al-Babili S^#. Methyl phenlactonoates are efficient strigolactone analogs with simple structure.

J Exp Bot

. 2018, 69(9):2319-2331. （中科院1区）

Miyazaki S, Jiang K, Kobayashi M, Asami T, Nakajima M^#. Helminthosporic acid functions as an agonist for gibberellin receptor.

Biosci Biotechnol Biochem

. 2017, 81(11):2152-2159. （中科院4区）

小分子化合物在促进植物损伤后再生中应用，申请日 2025.04.14，申请号 2025104641116（发明人：姜凯；程靓；房子坚；刘双源；唐永圆；于樾）

吲哚-3-丙酮酸在制备治疗抗癌症药物中的应用，申请日 2023.02.27，申请号 CN202310212070.2（发明人：胡海亮；郭红卫；李桑桑；杜长征；姜凯）

小分子化合物在促进植物生长发育中的应用，授权日 2022.02.15，ZL202110040713.0（发明人：郭红卫；谢银鹏；姜凯；朱颖）

杂环苯甲酰胺类化合物及其在促进植物生长发育中的应用，授权日 2024.07.19，ZL 2022 1 0064182.3（发明人：郭红卫；姜凯；谢银鹏）

PIFs的暗处稳定剂在促进双子叶植物顶端弯钩发育中的应用，授权日 2023.01.03，ZL202110581494.4（发明人：郭红卫；亚立坤疆·艾则孜；姜凯）

NRT1.7基因表达的抑制剂在制备衣霉素吸收抑制剂中的应用，授权日 2023.03.24，ZL202110678271.2（发明人：郭红卫；刘传发；姜凯；温兴）

一种土甘草提取物在制备果蔬保鲜剂中的应用，授权日 2024.02.27，ZL202011596465.X（发明人：吴无畏；郭红卫；蓝鸣生；姜凯；陈路；张琳琳；刘钰；秦明珍）

防治水稻稻瘟病和纹枯病的芽胞杆菌菌株，授权日 2012.05.30，ZL201010028132.7（发明人：徐正君；姜凯；李利华；高晓玲；高鸿；张小平；马炳田；徐永菊；山口五十磨；朱建清；邓小建；钟凯；王平荣；黄静）